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Olanexidine hydrochloride

CAS No. 146509-94-6

Olanexidine hydrochloride( —— )

Catalog No. M34354 CAS No. 146509-94-6

Olanexidine hydrochloride (OPB-2045 HCl) shows bactericidal activity against Gram-positive and Gram-negative bacteria. Olanexidine hydrochloride disrupts the membrane integrity of S. aureus.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 132 Get Quote
10MG 188 Get Quote
25MG 394 Get Quote
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Biological Information

  • Product Name
    Olanexidine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Olanexidine hydrochloride (OPB-2045 HCl) shows bactericidal activity against Gram-positive and Gram-negative bacteria. Olanexidine hydrochloride disrupts the membrane integrity of S. aureus.
  • Description
    Olanexidine hydrochloride is a monobiguanide compound with bactericidal activity. Olanexidine probably binds to the cell membrane, destroys membrane integrity. Olanexidine hydrochloride is active against a wide range of bacteria, including Gram-positive and Gram-negative bacteria. Olanexidine exhibits the bactericidal concentration of 109 μg/mL for Gram-positive bacilli.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    146509-94-6
  • Formula Weight
    408.8
  • Molecular Formula
    C17H28Cl3N5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (152.89 mM; Ultrasonic (<60°C); )
  • SMILES
    Cl.CCCCCCCCNC(=N)NC(=N)NCc1ccc(Cl)c(Cl)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hagi A, et al. Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic. Antimicrob Agents Chemother. 2015 Aug;59(8):4551-9. ?
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